~ Archive for May 23, 2006 ~

Cisplatin, Pemetrexed and Bevacizumab for Untreated Malignant Mesothelioma

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From the National Cancer Institute, I see there is a new clinical trial starting for mesothelioma treatment.  This one uses three of the big chemotherapy drugs in this field: the old standby cisplatin (one of the workhorses of chemotherapy over the past 30 years), pemetrexed (the new and promising mesothelioma drug) and bevacizumab (the first FDA approved anti-angiogenesis agent and an exciting drug in many areas of oncology.)  The researchers are looking to test this cocktail of agents on mesothelioma patients who have never had any treatment for their cancer - who are chemically “naive” as they say.  It should be interesting to see what results from this triple-threat to mesothelioma tumors.

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